Table 3.
2018 Definition of periprosthetic hip and knee infection: (CRP (C-reactive protein), ESR (Erythrocyte sedimentation rate), LE (leucocyte esterase), PMN (polymorphonuclear leukocyte), AD-1 (alpha-1-defensin))
| Major criteria (at least one of the following | Decision | |
|---|---|---|
| Two positive cultures of the same organism | Infected | |
| Sinus tract with evidence of the communication to the joint or visualization of the prosthesis | ||
| Minor criteria | Score | Decision |
| Elevated serum CRP or D-Dimere | 2 | ≥6 Infected |
| Elevated serum ESR | 1 | |
| Elevated synovial WBC or LE (++) | 3 | 2–5 Possibly |
| Positive Alpha-Defensin | 3 | Infected |
| Elevated synovial PMN | 2 | |
| Elevated synovial CRP | 1 | 0–1 Not Infected |
| Inconclusive pre-op Score or dry tap | Score | Decision |
| Preoperative Score | – | ≥6 Infected |
| Positive Histology | 3 | |
| Positive Purulence | 3 | 4–5 Inconclusive |
| Positive Single Culture | 2 | ≤3 Not Infected |