Fig. 5.

l-CDL decreased CCI-upregulated expression of p-ERK, p-JNK, p-p38, p-p65 and TNF-α, IL-1β in the DRG and sciatic nerve of CCI rats. The expression of p-ERK, p-p38 (a, d), p-JNK, p-p65 (b, e), TNF-α, and IL-1β (c, f) in the DRG and sciatic nerve in CCI rats after l-CDL (1.5, 3, 6 mg/kg) was intramuscularly injected around the sciatic nerve. n = 4 per group; #P < 0.05, ##P < 0.01, and ###P < 0.001, compared with the control group; *P < 0.05, **P < 0.01, and ***P < 0.001, compared with the CCI group