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. Author manuscript; available in PMC: 2020 Apr 21.
Published in final edited form as: Expert Opin Pharmacother. 2017 May 19;18(8):825–832. doi: 10.1080/14656566.2017.1328056
Degarelix LHRH agonist
Rapid testosterone suppression (~3days) Prolonged suppression of testosterone (10-20days)
No initial testosterone flare Initial testosterone flare
No microsurges of testosterone Microsurges of testosterone with each injection
Complete FSH suppression Partial FSH suppression
Monthly maintenance injection 3-6 month maintenance injection schedule