Table 3.
Variables | HR | 95% CI | p-value |
---|---|---|---|
Male | 0.605 | 0.184–1.985 | 0.407 |
Over 30 years old | 0.664 | 0.179–2.458 | 0.540 |
Baseline ALT > 4 × ULN U/L | 17.241 | 1.689–166.667 | 0.016 |
Baseline HBV DNA < 2 × 106 IU/mL | 7.813 | 1.961–31.250 | 0.004 |
Baseline HBsAg < 25,000 IU/mL | 1.624 | 1.083–2.435 | 0.019 |
On-treatment HBsAg decline > 1 log10IU/mL at week 24 | 55.556 | 11.904–250 | < 0.001 |
On-treatment HBV DNA decline > 2 log10IU/mL at week 24 | 14.084 | 3.003–66.667 | 0.001 |
Duration of IFN over 1 year | 2.140 | 0.680–6.736 | 0.193 |
ALT alanine aminotransferase, ULN upper limit of normal, IFN interferon. P-values < 0.05 are shown in bold italics