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. 2020 Feb 24;55(3):254–263. doi: 10.1093/alcalc/agaa010

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© The Author(s) 2020. Medical Council on Alcohol and Oxford University Press. All rights reserved.

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Fig 3. — The effects of cocaine (20 mg/kg) and AMP/SUL (100 and 200 mg/kg) on GLT-1/β-tubulin (A), xCT/β-tubulin (B) and GLAST/β-tubulin (C) in the NAc core following 4-day ethanol re-exposure (mean ± SEM). One-way ANOVA revealed a significant reduction in GLT-1/β-tubulin and xCT/β-tubulin in the ethanol-cocaine-saline-treated group and an increase in GLT-1/β-tubulin and xCT/β-tubulin in the ethanol-cocaine–AMP/SUL (200 mg/kg) treated group. No significant difference was revealed in GLAST/β-tubulin between groups. (*P < 0.05, **P < 0.01 and ***P < 0.001), (n = 5–7 for each group). Abbreviations: WS, water-saline; ES, ethanol-saline; ECS, ethanol-cocaine-saline; ECA/S-1, ethanol-cocaine-AMP/SUL 100; and ECA/S-2, ethanol-cocaine-AMP/SUL 200.