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Summary of future challenges and opportunities in islet miRNA research. The diagram illustrates miRNA biogenesis from gene to the mature form, the miRNA–mRNA interaction network, and the processes influenced by miRNAs in the β-cell (β-cell identity, β-cell proliferation/apoptosis, and β-cell physiology). For each field of these biological processes involving miRNAs, we have added the four areas of challenges and opportunities discussed in the text. pri-miRNA, primary miRNA.
