Table 2.

Serum cytokine profile during sepsis

Cytokine (pg/ml)	Vehicle sham	Vehicle CLP	FtH−/− CLP	FtL CLP
IFNγ	0.23±0.03	4.58±0.84	0.58±0.09	0.56±0.16
IL-1β	1.15±0.08	34.35±7.37	2.31±0.31	3.098±1.1
IL-2	0.54±0.09	27.18±5.07	1.09±0.33	0.47±0.11
IL-4	undet	13.16±4.09	0.89±0.37	0.44±0.17
IL-5	6.3±1.76	12.9±1.78	6.48±2.8	4.3±1.67
IL-6	152±23.9	28905±3191	2045±300	1701±514
IL-10	17.28±2.5	3075±711	49.43 ±5.32	292±125
IL-12	undet	1229±330	88.53±14.3	49.4±11.4
CXCL1	278.4±53	5466±238	2790±472	1306±376
TNFα	16.15±2.9	517±83	453±174	60.87±24

Abbreviations: CLP, cecal ligation and puncture; FtH^−/−, ferritin heavy chain knockout; FtL, ferritin light chain; undet, undetectable levels. Adapted with permission.⁹²