Table 2.
Definitions of variables included in the models and coefficients for the fitted flow-independent model (model A). The column “response” refers for the hemodynamic to the type of response-variable (see Fig. 2)
| Variable | Type | Definition | Response | Coefficient |
|---|---|---|---|---|
| age | Patient | Patient age | / | −0.0180 |
| sex.F | Patient | Female patient | / | −0.1869 |
| sex.M | Patient | Male patient | / | 0.1869 |
| Avol | Shape | Aneurysm volume | / | 0 |
| Asize | Shape | Aneurysm size = max. distance between any two points on the aneurysm surface | / | 0 |
| Aarea | Shape | Aneurysm area | / | 0 |
| Nsize | Shape | Max. distance between any two points on the neck surface | / | 0 |
| Narea | Shape | Area of the neck surface | / | −0.4993 |
| depth | Shape | / | 0 | |
| AR | Shape | Aspect ratio = aneurysm depth/neck diameter | / | 0 |
| Aheight | Shape | Max. normal distance of all points on aneurysm dome from aneurysm neck | / | 0 |
| Awidth | Shape | Max. diameter of aneurysm slices parallel to aneurysm neck | / | −1.1558 |
| HWR | Shape | Height to width ratio = aneurysm height/aneurysm width | / | 0.3583 |
| Ndiam | Shape | Equivalent diameter of neck = 4*area/perimeter | / | 0 |
| Aspect | Shape | Aspect ratio 2 = aneurysm height/neck diameter | / | 0 |
| BF | Shape | Bottle neck factor = aneurysm width/neck diameter | / | 0 |
| BL | Shape | Bulge location = Distance of plane with largest diameter from neck/height | / | 0.1624 |
| Vdiam | Shape | Vessel diameter: diameter of nearest vessel from aneurysm neck | / | −1.714 |
| SizeR | Shape | Size ratio = aneurysm size/vessel diameter | / | 0 |
| VOR | Shape | Volume to ostium ratio = Aneurysm volume/Area of neck | / | −0.0841 |
| CR | Shape | Convexity ratio = aneurysm volume/volume of aneurysm’s convex hull | / | 0 |
| IPR | Shape | Isoperimetric ratio | / | 0 |
| EI | Shape | Ellipticity inde | / | 0 |
| NSI | Shape | Non-sphericity index | / | 5.4401 |
| GAA | Shape | Area weighted average of Gaussian aneurysm surface curvature | / | −0.0050 |
| MAA | Shape | Area weighted average of mean curvature | / | 0 |
| GLN | Shape | L2-Norm of Gaussian curvature | / | 0 |
| MLN | Shape | L2-Norm of mean aneurysm surface curvature | / | 6.3289 |
| ICI | Hemod. | Inflow concentration index | Linearity | −0.0068 |
| Mean | 0.2211 | |||
| Q | Hemod. | Mean inflow rate into aneurysm | Linearity | −1.0297 |
| Mean | 0 | |||
| KE | Hemod. | Mean kinetic energy | Linearity | 0 |
| Mean | 0.0004 | |||
| SR | Hemod. | Mean shear rate | Linearity | 0 |
| Mean | 0 | |||
| VE | Hemod. | Mean velocity | Linearity | 0 |
| Mean | 0 | |||
| VO | Hemod. | Mean vorticity | Linearity | 0 |
| Mean | 0 | |||
| VD | Hemod. | Mean viscous dissipation | Linearity | 0 |
| Mean | 0 | |||
| WSSmax | Hemod. | Maximum wall shear stress | Linearity | 0 |
| Mean | 0 | |||
| WSSmin | Hemod. | Minimum wall shear stress | Linearity | −0.2260 |
| Mean | 0 | |||
| WSSmean | Hemod. | Mean wall shear stress | Linearity | 0 |
| Mean | 0 | |||
| LSA | Hemod. | Low shear area | Linearity | −0.3474 |
| Mean | 0 | |||
| SCI | Hemod. | Shear concentration index | Linearity | −0.1698 |
| Mean | 0 | |||
| WSSves | Hemod. | Mean wall shear stress in parent vessel | Linearity | 13.7839 |
| Mean | 0.0056 | |||
| WSSnorm | Hemod. | Normalized WSS = WSSmean/WSSves | Linearity | 0 |
| Mean | 0 | |||
| MWSSnorm | Hemod. | Maximum normalized WSS = WSSmax/WSSves | Linearity | −0.0165 |
| Mean | 0.0104 | |||
| corelen | Hemod. | Vortex core line length (characterizes flow complexity) | Linearity | 0.1294 |
| Mean | 0 | |||
| Vmax | Hemod. | Peak velocity | Linearity | 0 |
| Mean | 0.0010 | |||
| position.ACA | Location | Anterior cerebral artery | / | 0.3429 |
| position.ACOM | Location | Anterior communicating artery | / | 1.2983 |
| position.BA-DIST-PROX | Location | Basilar artery other than tip | / | −0.1379 |
| position.BA-TIP | Location | Tip of basilar artery | / | 0.4223 |
| position.ICA-ACHOR | Location | Internal carotid artery - anterior choroidal | / | −0.3199 |
| position.ICA-BIF | Location | Internal carotid artery bifurcation | / | −0.3582 |
| position.ICA-CAV | Location | Cavernous internal carotid artery | / | −1.1614 |
| position.ICA-OPH | Location | Internal carotid artery - ophthalmic | / | −0.7665 |
| position.ICA-SHYP | Location | Superior hypophyseal segment internal carotid artery | / | −0.1910 |
| position.MCA-BIF | Location | Middle cerebral artery bifurcation | / | 0.1154 |
| position.MCA-DIST-PROX | Location | Middle cerebral artery other than bifurcation | / | −0.8805 |
| position.PCOM | Location | Posterior communicating artery | / | 0.9078 |
| position.VA | Location | Vertebral artery | / | 0.7287 |