Table 4. MACM Summary Table.
Individual MACM analysis shows brain-wide functional co-activation clusters. Clusters represent regions of statistically significant convergence of co-activation foci as reported in the BrainMap database. Statistical significance is reported as ALE score (Eickhoff, et al., 2012).
| a. Patient 1 | ||||||
|---|---|---|---|---|---|---|
| Cluster # | Volume (mm^3) | ALE Score (x10) | Weighted Center MNI152 (x,y,z) |
Talairach Label | ||
| 1 | 32384 | 3.6972487 | −48 | 32 | 22 | Left Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 46 |
| 2 | 14560 | 0.9527298 | 48 | 38 | 24 | Right Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 9 |
| 3 | 11616 | 0.85477084 | 2 | 26 | 42 | Left Cerebrum.Frontal Lobe.Medial Frontal Gyrus.Gray Matter.Brodmann area 8 |
| 4 | 10872 | 0.95113054 | −42 | −44 | 44 | Left Cerebrum.Parietal Lobe.Inferior Parietal Lobule.Gray Matter.Brodmann area 40 |
| 5 | 5056 | 0.70201054 | 34 | −62 | 50 | Right Cerebrum.Parietal Lobe.Superior Parietal Lobule.Gray Matter.Brodmann area 7 |
| 6 | 3960 | 0.5746817 | −50 | −62 | −2 | Left Cerebrum.Temporal Lobe.Inferior Temporal Gyrus.Gray Matter.Brodmann area 19 |
| 7 | 2536 | 0.8662599 | 34 | 22 | 0 | Right Cerebrum.Sub-lobar.Claustrum.Gray Matter. |
| 8 | 2200 | 0.4513255 | −28 | 8 | 56 | Left Cerebrum.Frontal Lobe.Sub-Gyral.Gray Matter.Brodmann area 6 |
| 9 | 2080 | 0.43759383 | −12 | −12 | 6 | Left Cerebrum.Sub-lobar.Thalamus.Gray Matter.Ventral Lateral Nucleus |
| 10 | 2056 | 0.5204129 | 30 | 2 | 48 | Right Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 6 |
| 11 | 888 | 0.4587746 | 10 | −10 | 8 | Right Cerebrum.Sub-lobar.Thalamus.Gray Matter. |
| 12 | 432 | 0.47315214 | 50 | 20 | −6 | Right Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 47 |
| 13 | 320 | 0.36938224 | 58 | −56 | −12 | Right Cerebrum.Temporal Lobe.Inferior Temporal Gyrus.Gray Matter.Brodmann area 20 |
| 14 | 320 | 0.45044336 | −20 | −100 | −2 | Left Cerebrum.Occipital Lobe.Lingual Gyrus.Gray Matter.Brodmann area 18 |
| b. Patient 2 | ||||||
| Cluster # | Volume (mm^3) | ALE Score (x10) | Weighted Center MNI152 (x,y,z) |
Talairach Label | ||
| 1 | 15712 | 3.1472412 | −48 | 26 | 30 | Left Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 9 |
| 2 | 7880 | 0.6158217 | −34 | −52 | 46 | Left Cerebrum.Parietal Lobe.Inferior Parietal Lobule.Gray Matter.Brodmann area 40 |
| 3 | 6840 | 0.77475175 | −4 | 26 | 42 | Left Cerebrum.Limbic Lobe.Cingulate Gyrus.Gray Matter.Brodmann area 32 |
| 4 | 5856 | 0.4794898 | 48 | 18 | 30 | Right Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 9 |
| 5 | 2720 | 0.7074343 | −30 | 22 | −2 | Left Cerebrum.Sub-lobar.Claustrum.Gray Matter. |
| 6 | 1976 | 0.49369562 | −46 | −52 | −22 | Left Cerebellum.Anterior Lobe.Culmen.Gray Matter. |
| 7 | 1944 | 0.47308784 | 30 | −92 | −6 | Right Cerebrum.Occipital Lobe.Inferior Occipital Gyrus.Gray Matter.Brodmann area 18 |
| 8 | 1880 | 0.59526917 | −18 | −96 | −8 | Left Cerebrum.Occipital Lobe.Inferior Occipital Gyrus.Gray Matter.Brodmann area 17 |
| 9 | 1728 | 0.63747704 | 34 | 22 | 0 | Right Cerebrum.Sub-lobar.Claustrum.Gray Matter. |
| 10 | 1512 | 0.53964928 | −28 | 6 | 58 | Left Cerebrum.Frontal Lobe.Sub-Gyral.Gray Matter.Brodmann area 6 |
| 11 | 1376 | 0.37447874 | 30 | −66 | 42 | Right Cerebrum.Parietal Lobe.Precuneus.Gray Matter.Brodmann area 7 |
| 12 | 640 | 0.40365443 | −40 | 48 | 4 | Left Cerebrum.Frontal Lobe.Middle Frontal Gyrus.Gray Matter.Brodmann area 10 |
| 13 | 408 | 0.34802593 | −46 | 30 | 0 | Left Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 13 |
| 14 | 400 | 0.40031504 | 10 | −10 | 10 | Right Cerebrum.Sub-lobar.Thalamus.Gray Matter. |
| 15 | 280 | 0.33685982 | −20 | 0 | 6 | Left Cerebrum.Sub-lobar.Lentiform Nucleus.Gray Matter.Putamen |
| 16 | 272 | 0.4005287 | 6 | 12 | 0 | Right Cerebrum.Sub-lobar.Caudate.Gray Matter.Caudate Head |
| 17 | 272 | 0.36310226 | −50 | 14 | 2 | Left Cerebrum.Sub-lobar.Insula.Gray Matter.Brodmann area 13 |
| 18 | 232 | 0.37760735 | −50 | −64 | 0 | Left Cerebrum.Temporal Lobe.Middle Temporal Gyrus.Gray Matter.Brodmann area 37 |
| 19 | 224 | 0.32760523 | 54 | 10 | 18 | Right Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 44 |
| c. Patient 3 | ||||||
| Cluster # | Volume (mm^3) | ALE Score (x10) | Weighted Center MNI152 (x,y,z) |
Talairach Label | ||
| 1 | 39384 | 3.9066708 | −50 | 28 | −8 | Left Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 47 |
| 2 | 10104 | 0.8000214 | 48 | 28 | −10 | Right Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 47 |
| 3 | 9824 | 0.9233824 | −2 | 14 | 54 | Left Cerebrum.Frontal Lobe.Superior Frontal Gyrus.Gray Matter.Brodmann area 6 |
| 4 | 6736 | 1.1416699 | −56 | −42 | 0 | Left Cerebrum.Temporal Lobe.Middle Temporal Gyrus.Gray Matter.Brodmann area 22 |
| 5 | 2072 | 0.55852685 | −44 | −52 | −20 | Left Cerebellum.Anterior Lobe.Culmen.Gray Matter.* |
| 6 | 2032 | 0.673141 | −20 | −6 | −16 | Left Cerebrum.Limbic Lobe.Parahippocampal Gyrus.Gray Matter.Amygdala |
| 7 | 1480 | 0.6643619 | −8 | 60 | 24 | Left Cerebrum.Frontal Lobe.Superior Frontal Gyrus.Gray Matter.Brodmann area 9 |
| 8 | 1376 | 0.5034907 | 54 | −20 | −6 | Right Cerebrum.Temporal Lobe.Superior Temporal Gyrus.Gray Matter.Brodmann area 22 |
| 9 | 1016 | 0.5651355 | −8 | 48 | 40 | Left Cerebrum.Frontal Lobe.Superior Frontal Gyrus.Gray Matter.Brodmann area 8 |
| 10 | 880 | 0.48787095 | −32 | −52 | 46 | Left Cerebrum.Parietal Lobe.Inferior Parietal Lobule.Gray Matter.Brodmann area 40 |
| 11 | 408 | 0.47318645 | −2 | −48 | 30 | Left Cerebrum.Limbic Lobe.Cingulate Gyrus.Gray Matter.Brodmann area 31 |
| 12 | 384 | 0.4897453 | 24 | −2 | −18 | Right Cerebrum.Limbic Lobe.Parahippocampal Gyrus.Gray Matter.Amygdala |
| d. Conjunction Analysis for P1, P2, P3 | ||||||
| Cluster # | Volume (mm^3) | ALE Score (x10) | Weighted Center MNI152 (x,y,z) |
Talairach Label | ||
| 1 | 2198 | 0.124 | −48 | 19 | 27 | Left Cerebrum.Frontal Lobe.Middle Frontal Gyrus.White Matter.* |
| 2 | 1113 | 0.0705 | 1 | 22 | 44 | Paracingulate Gyrus, Cingulate Gyrus |
| 3 | 205 | 0.0463 | −29 | −56 | 48 | Left Cerebrum.Parietal Lobe.Superior Parietal Lobule.White Matter.* |
| 4 | 180 | 0.047 | 41 | 23 | −3 | Right Cerebrum.Sub-lobar.Insula.Gray Matter.Brodmann area 13 |
| 5 | 172 | 0.0394 | 57 | 27 | 21 | Right Cerebrum.Frontal Lobe.Inferior Frontal Gyrus.Gray Matter.Brodmann area 9 |
| 6 | 124 | 0.0409 | −46 | −56 | −13 | Left Cerebrum.Temporal Lobe.Fusiform Gyrus.White Matter.* |
| 7 | 64 | 0.0315 | −52 | 15 | 3 | Left Cerebrum.Frontal Lobe.Precentral Gyrus.Gray Matter.Brodmann area 44 |
| 8 | 8 | 0.0177 | 54 | 40 | 14 | Right Cerebrum.Frontal Lobe.Middle Frontal Gyrus.White Matter.* |