Table 2:
Summary of all the identified toxin-like genes from the genome of the jellyfish R. esculentum
| Gene | Copy No. | Description | Family | Reported in jellyfish |
|---|---|---|---|---|
| Phospholipase A2 | 9 | Phospholipase A2 activity | Phospholipase A2 family | Yes |
| Acidic phospholipase A2 PA4 | 4 | Phospholipase A2 activity | Phospholipase A2 family | Yes |
| Phospholipase A2 isozymes PA3A/PA3B/PA5 | 4 | Phospholipase A2 activity | Phospholipase A2 family | Yes |
| Putative phospholipase B-like 2 | 1 | Hydrolase activity | Phospholipase B-like family | Yes |
| Zinc metalloproteinase nas | 39 | Metalloendopeptidase activity | Yes | |
| Disintegrin and metalloproteinase | 21 | Metalloendopeptidase activity | Yes | |
| Ectonucleotide pyrophosphatase/phosphodiesterase | 8 | Nuclease activity | Nucleotide pyrophosphatase/phosphodiesterase family | Yes |
| 5′-Nucleotidase | 5 | 5′-Nucleotidase activity | 5′-Nucleotidase family | Yes |
| Serine carboxypeptidase | 1 | Serine-type carboxypeptidase activity | Peptidase S10 family | Yes |
| Serine protease | 7 | Serine-type endopeptidase activity | Peptidase S1 family | Yes |
| Prothrombin | 2 | Serine-type endopeptidase activity | Peptidase S1 family | Yes |
| Dipeptidyl peptidase 9 | 1 | Serine-type peptidase activity | Peptidase S9B family | Yes |
| Kunitz-type serine protease inhibitor | 1 | Serine-type endopeptidase inhibitor activity | Venom Kunitz-type family | Yes |
| Cystatin | 1 | Cysteine-type endopeptidase inhibitor activity | Cystatin family | Yes |
| Plancitoxin-1 | 3 | Toxin activity | DNase II family | Yes |
| Ryncolin | 6 | Toxin activity | Ficolin lectin family | Yes |
| Toxin TX | 2 | Toxin activity | Jellyfish toxin family | Yes |
| Trpa1 | 1 | Toxin activity | (High similarity with α-latrotoxin-Lt1a) | Yes |
| Peroxiredoxin-4 | 2 | Protein homodimerization activity | Peroxiredoxin family | Yes |
| Glutaminyl-peptide cyclotransferase-like protein | 1 | Glutaminyl-peptide cyclotransferase activity | Glutaminyl-peptide cyclotransferase family | Yes |
| Lysosomal acid lipase/cholesteryl ester hydrolase | 1 | Lipase activity | Lipase family | Yes |
| Trehalase | 1 | α-trehalase activity | Glycosyl hydrolase 37 family | Yes |
| Acetylcholinesterase | 1 | Acetylcholinesterase activity | Type-B carboxylesterase/lipase family | Yes |
| Lysosomal acid phosphatase | 1 | Acid phosphatase activity | Histidine acid phosphatase family | No |
| Reticulocalbin | 1 | Calcium ion binding | CREC family | No |
| Translationally controlled tumour protein homolog | 1 | Calcium ion binding | TCTP family | Yes |
| Hyaluronidase-1 | 2 | Hyaluronan synthase activity | Glycosyl hydrolase 56 family | Yes |
Full gene names are provided in Supplementary Table S12.