Table 1.
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| Pediatric patients no. (%) | Pediatric patients no. (%) | |
|---|---|---|
| Demographics | ||
| Number of subjects | 32 (88.8%) | 4 (12.2%) |
| Median age (range) | 12 months (24 days to 8 years) | 58 years (20–86 years) |
| Male | 22 (66.7%) | 2 (50%) |
| African-American | 10 (31.3%) | 2 (50%) |
| Caucasion | 17 (53.1%) | 2 (50%) |
| Underlying conditions | ||
| Prematurity (<37 weeks) | 10 (31.3%) | N/A |
| Cardiac diseasea | 6 (18.8%) | 2 (50%) |
| Immunodeficiencyb | 3 (9.3%) | 0 |
| Pulmonary diseasec | 3 (9.3%) | 4 (100%) |
| Clinical signs and symptoms | ||
| Respiratory findingsd | 28 (87.5%) | 3 (75%) |
| Cough | 24 (75.0%) | 2 (50%) |
| Rhinorrhea | 20 (62.5%) | 2 (50%) |
| Fever > 38.0 °C | 17 (53.1%) | 1 (25%) |
| Tachycardia | 13 (40.6%) | 0 |
| Gastrointestinal symptoms | 11 (34.3%) | 0 |
| Hospitalization | ||
| Hospitalized | 27 (84.4%) | 4 (100%) |
| Median hospital days (range) | 3 days (1–8 days) | 1.5 days (1–4 days) |
| Admitted to ICU | 9 (28.1%) | 0 |
| Median ICU days (range) | 2 days (1–5 days) | N/A |
| Oxygen therapy | 10 (31.3%) | 0 |
Pediatric diagnoses include multifocal atrial tachycardia, ventricular septal defect,atrial septal defect, patent ductus arteriosus, and hypoplastic left heart. In adults, diagnoses include heart failure, atrial fibrillation/flutter, and prosthetic mitral and tricuspid values.
Include Kippel–Feil syndrome with asplenia, neutropenia secondary to chemotherapy, and common variable immune deficiency.
In pediatric patients, excludes lung disease associated with prematurity. Includes asthma and Hunter's disease. In adults, includes asthma, chronic obstructive pulmonary disease, transudative pleural effusion, and restrictive lung disease.
Specific respiratory findings (number, %) -Pediatric patients respiratory distress (13, 40.6%), hypoxia (9, 28.1%), ronchi (10, 31.2%), wheeze (8, 25.0%), tachypnea (8, 25.0%), rales (7, 21.8%), cyanosis (4, 12.5%), apnea (3, 9.3%). Adult patients: tachypnea (3, 75%), wheeze (2, 50%), rales (1, 25%), and hypoxia (1, 25%).