Table 3.
Accuracy of microbiological tests for the diagnosis of pneumonia
Comprehensive molecular testing | Viral PCR | Bacterial PCR | Routine methods | |
---|---|---|---|---|
Sensitivity | 61% (53–69) | 35% (28–44) | 39% (31–48) | 14% (82–21) |
Specificity | 50% (39–61) | 76% (65–85) | 68% (57–78) | 94% (86–98) |
Positive predictive value | 68% (62–74) | 73% (62–81) | 68% (59–76) | 81% (61–93) |
Negative predictive value | 42% (35–50) | 40% (36–45) | 39% (34–44) | 38% (36–41) |
Positive likelihood ratio | 1.23 (0.94–1.61) | 1.50 (0.93–2.42) | 1.23 (0.83–1.84) | 2.55 (0.90–7.25) |
Negative likelihood ratio | 0.77 (0.56–1.06) | 0.85 (0.70–1.01) | 0.90 (0.72–1.10) | 0.91 (0.83–0.99) |
Diagnostic odds ratio | 1.59 (0.89–2.85) | 1.77 (0.92–3.41) | 1.38 (0.75–2.55) | 2.81 (0.91–8.65) |