Table 2.

Changes in medical management in children and adults by diagnostic method.

	Univariate Analysis					Multivariate Analysisa		Multivariate Analysisb
	FilmArray-RP		IFA		p	OR (CI95%)	p	OR (CI95%)	p
	n	(%)	n	(%)
Children	113		43
Total n of children with a medical change	62	(54.8)	6	(13.9)	<0.001	7.77 (3.02–20.03)	<0.001	8.07 (3.03–21.47)	<0.001
Decrease in antibiotic prescriptions	26	(23.0)	1	(2.3)	0.001	13.17 (1.71–101.01)	0.013	12.23 (1.56–96.09)	0.017
Increase in antibiotic prescriptions	2	(1.8)	1	(2.3)	0.697
Decrease in oseltamivir prescriptions	2	(1.8)	1	(2.3)	0.621
Increase in oseltamivir prescriptions	2	(1.8)	1	(2.3)	0.621
Decrease in complementary studies	29	(25.7)	2	(4.7)	0.001	6.84 (1.53–30.49)	0.012	9.64 (2.13–43.63)	0.003
Increase in complementary studies	6	(5.1)	0	(0.0)	0.087
Adults	176		100
Total n of adults with a medical change	55	(31.3)	14	(14.0)	0.001	2.60 (1.35–5.01)	0.004	2.67 (1.32–5.40)	0.006
Decrease in antibiotic prescriptions	24	(13.6)	1	(1.0)	0.001	15.90 (2.10–119.96)	0.007	15.52 (1.99–120.83)	0.009
Increase in antibiotic prescriptions	2	(1.1)	1	(1.0)	0.657
Decrease in oseltamivir prescriptions	21	(11.9)	9	(9.0)	0.042	1.19 (0.51–2.79)	0.683
Increase in oseltamivir prescriptions	12	(6.8)	3	(3.0)	0.091
Decrease in complementary studies	1	(0.6)	0	(0.0)	0.594
Increase in complementary studies	0	(0.0)	1	(1.0)	0.364
Total n patients with a medical change	117	(40.5)	20	(14.0)	<0.001	4.21 (2.48–7.16)	<0.001	4.35 (2.49–7.60)	<0.001

FilmArray-RP: BioFire FilmArray respiratory panel, IFA: immunofluorescence assay, OR: odds ratio, CI: confidence interval, n = number, p values <0.05 in bold.

^aLogistic regression model adjusted for sex and age.

^bLogistic regression model adjusted for sex, age and randomization.