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Schematic diagrams of each vaccine tested. Foreign epitope sequences are indicated for the MIR, the N-terminus, and the C-terminus of the HBcAg protein as well as their location within the vector protein. Additional mutations are reported at their approximate location. (A) The truncated HBcAg protein with an N-terminal Histidine tag; (B–D) treatment vaccines used during the first animal trial; (E–G) treatment vaccines used during the second animal trial.
