Fig. 5.

Antibody titers to the vector protein and Histidine tag. Ab titers from mouse sera after completion of both animal trials as measured by ELISA corresponding to plates coated with His6xΔHBcAg (A and B) or His6xAP205 (C and D) are shown. Sera were tested for the presence of Abs after the first animal trial (A and C) as well as the second animal trial (B and D). Each treatment group’s mean titer is compared to the ΔHBcAg negative control by ANOVA analysis. Standard error bars are shown for each treatment group (^* = P ≤ 0.05, ^** = P ≤ 0.01, ^*** = P ≤ 0.001).