Fig. 6.

VN and WV ELISA. A foci forming assay (FFA) and a whole virus ELISA were used to determine the serum Ab titers specific to the CO strain of PEDV. Sera collected at Day 42 for each treatment group from (A) the first animal trial and (B) the second animal trial were tested for PEDV neutralization in vitro. These same serum samples were subsequently tested for their ability to bind to PEDV without neutralization measurement (C). Each treatment group’s mean titer is compared to both the ΔHBcAg and PBS Only negative controls by ANOVA analysis. Standard error bars are shown for each treatment group (^* = P ≤ 0.05, ^** = P ≤ 0.01, ^*** = P ≤ 0.001).