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. 2009 Sep 23;16(2):192–198. doi: 10.1016/j.bbmt.2009.09.014

Table 1.

Patient Characteristics

Patient
1 2 3 4 5 6 7 8 9 10 11 12 13
Age, years 42 29 65 32 58 48 65 49 40 55 56 52 72
Sex M M F M F F F M M M M M M
Treatment type MUD MUD Mini-MUD MUD Mini-MUD MUD Mini-MUD MUD MUD MUD MUD Sibling allogeneic Mini-MUD
Diagnosis PH + ALL CML CLL NHL AML AML MM CML AML NHL MDS NHL AML
ECOG 3 3 1 2 2 1 2 3 3 2 4 2 1
Graft-versus-host disease Chronic skin, lung, liver None None Chronic lung, sicca syndrome None None None Chronic lung Chronic lung, eye, skin Chronic liver None Acute skin Pretransplantation
Prednisone >20 mg Yes Yes No No No Yes No Yes No Yes Yes Yes No
Duration of symptoms before diagnosis 5 days Asymptomatic 24 hours 7 days 5 days 3 days 4 days > 1 month 10 days Unknown 1 month 24 hours 2-3 days
Time after treatment/engraftment status 3 years/+ 14 days/- 6 days/- 2 years/+ 17 days/+ 48 days/+ 25 days/+ 8 months/+ 4.7 years/+ 132 days/+ 38 days/+ 45 days/+ Pretransplantation
Pulmonary status History of Pseudomonas pneumonia 3/04, 8/04, 3/05; 2 L O2 O2 saturation 96% on RA; chest x-ray/computed tomography changes; crackles O2 saturation 99% on RA History of BOOP, O2 saturation 97% on RA O2 saturation 90%-92% on RA O2 saturation 99% on RA O2 saturation 96% on RA History of cytomegalovirus pneumonia 4/05; O2 saturation 97% on RA Concomitant infection with C. galbrata, C. guilliermondii, MRSA (BAL) On RA Presented with rapid-onset respiratory failure before BAL,? DAH with CMV + effusions O2 saturation 95% on RA O2 saturation 100% on RA
ALC 200 0 WBC 0.4 1000 200 400 500 1500 WBC 5.3
No differential
400 WBC 3.5
No differential
800 600
Ribavirin i.v., HD, i.v. IG No Inhaled × 5 days, i.v. × 3 days Inhaled × 7 days Inhaled × 7 days No No Inhaled × 7 days Oral × 18 days, i.v. × 3 days No Inhaled ×x 3 days, i.v. × 7 days No No
Symptoms LRTI LRTI LRTI LRTI LRTI URTI LRTI LRTI LRTI URTI LRTI URTI URTI
Outcome Expired Expired Recovered Expired Recovered Recovered Recovered Recovered Recovered Recovered Expired Recovered Recovered

BAL, Bronchoalveolar lavage, CML, chronic myelogenous leukemia; CLL, chronic lymphocytic leukemia; AML, acute myelogenous leukemia MUD, matched unrelated donor; MM, multiple myeloma MUD, matched unrelated donor; NHL, non-Hodgkin lymphoma.