Table IV.
Effect of concomitant characteristics at study entry for incidence of current asthma at age 8 years
| Risk factors | Current asthma at age 8 y |
|||||
|---|---|---|---|---|---|---|
| Any | P value | Atopic | P value | Nonatopic | P value | |
| Age 3-11 mo and no rhinovirus∗ | 13/38 (34) | 3/38 (8) | 10/38 (26) | |||
| Age 12-23 mo or rhinovirus | 14/53 (26) | .71 | 7/53 (13) | .11 | 7/53 (13) | .014 |
| Age 12-23 mo and rhinovirus | 10/36 (28) | 9/36 (25) | 1/36 (3) | |||
| No eczema and no sensitization† | 16/77 (21) | 3/77 (4) | 13/77 (17) | |||
| Eczema or any sensitization | 13/35 (37) | .003 | 8/35 (23) | <.001 | 5/35 (14) | .37 |
| Eczema and any sensitization | 7/10 (70) | 7/10 (70) | 0/10 (0) | |||
| No eczema and no rhinovirus | 10/47 (21) | 1/47 (2) | 9/47 (19) | |||
| Eczema or rhinovirus | 16/60 (27) | .018 | 9/60 (15) | <.001 | 7/60 (12) | .46 |
| Eczema and rhinovirus | 11/20 (55) | 9/20 (45) | 2/20 (10) | |||
| No sensitization and no rhinovirus | 14/56 (25) | 2/56 (4) | 12/56 (21) | |||
| Any sensitization or rhinovirus | 12/56 (24) | .015 | 6/50 (12) | <.001 | 6/50 (12) | .072 |
| Any sensitization and rhinovirus | 10/17 (59) | 10/17 (59) | 0/17 (0) | |||
| B-eos <0.4 × 109/L and no rhinovirus | 14/56 (25) | 3/56 (5) | 11/56 (20) | |||
| B-eos ≥0.4 × 109/L or rhinovirus | 12/38 (32) | .65 | 7/38 (18) | .015 | 5/38 (13) | .20 |
| B-eos ≥0.4 × 109/L and rhinovirus | 11/33 (33) | 9/33 (27) | 2/33 (6) | |||
| No parental asthma and no rhinovirus | 11/51 (22) | 3/51 (6) | 8/51 (16) | |||
| Parental asthma or rhinovirus | 20/59 (34) | .20 | 12/59 (20) | .038 | 8/59 (14) | .95 |
| Parental asthma and rhinovirus | 6/14 (43) | 4/14 (29) | 2/14 (14) | |||
| Age 12-23 mo with RSV or rhinovirus | 10/47 (21) | 9/47 (19) | 1/47 (2) | |||
| Age 3-11 mo or RSV/rhinovirus negative‡ | 20/66 (30) | .11 | 10/66 (15) | .21 | 10/66 (15) | <.001 |
| Age 3-11 mo and RSV/rhinovirus-negative | 7/14 (50) | 0/14 (0) | 7/14 (50) | |||
| Age 12-23 mo and no parental smoking | 7/33 (21) | 6/33 (18) | 1/33 (3) | |||
| Age 3-11 mo or parental smoking | 15/65 (23) | .004 | 7/65 (11) | .33 | 8/65 (12) | .003 |
| Age 3-11 mo and parental smoking | 15/27 (56) | 6/27 (22) | 9/27 (33) | |||
Values are shown as numbers (percentages) of subjects. P values were assessed by using χ2 or Fisher exact tests, indicating whole-group comparisons. Boldface and italic font indicate statistical significance.
B-eos, Blood eosinophil count.
∗
Alone or with other viruses, RSV included.
†
Defined as IgE antibodies to any of the common allergens. See the Methods section for details.
‡
With other viruses or no viruses.