Table 1.

Hyper-mutant (HM) sequences found in stool samples after RT-PCR of two VP1 regions.

Sample	Region 1 (341 bases)				Region 2 (409 bases)
	Total readsa	HM type	HM reads	Mutations/read (mean, min, max)	Total readsa	HM type	HM reads	Mutations/read (mean, min, max)
3106	99,176	A-to-G	12	7.2 (5–10)	96,415	U-to-C	39	5.5 (5–7)
3142	97,757	U-to-C	27	10.6 (5–30)	N/Ab	–	–	–
3210	N/Ab	–	–	–	96,770	U-to-C	13	5.6 (5–6)
3213	98,967	A-to-G	13	7.8 (5–12)	95,936	A-to-G	8	17.5 (6–37)

^aReads with an average base quality (Sanger-scaled Phred) score Q > 28 at mutated positions.

^bRT-PCR failed.