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ALV cytotoxicity. HepG2215 cells were treated with 0.25, 1, 5, and 20 μg/mL of ALV alone, in combination with 10 μmol/L of telbivudine (LdT) or 10 μmol/L of LdT alone. Supernatants were collected every 24 hours. LDH was measured by absorbance in HepG2215 treated with (A) ALV alone, (B) ALV/LdT, and in HBV-transfected HUH-7 treated with (C) ALV alone.
