Table 3.

Median Values and IQR for Each Parameter in All Patients, the Low Group (Less Than Median), and the High Group (Greater Than or Equal to the Median)^*

	All Patients			Low Group			High Group
Parameters	No.	Median	IQR	No.	Median	IQR	No.	Median	IQR
BMI, kg/m2	146	24.9	21.8–27.8	73	21.8	19.5–23.4	73	27.9	26.3–29.9
Age, yr	148	68.5	62.6–73.7	74	62.6	58.1–65.5	74	73.7	75.1–70.8
Fibrinogen, g/dL	130	3.95	3.52–4.42	65	3.53	3.15–3.83	65	4.42	4.09–4.80
FEV1%Pred	146	38.6	28.3–51.3	73	28.3	23.3–34.8	73	51.3	44.6–59.3
Sputum IL-6, pg/mL	90	99.6	24.0–223.8	45	24.0	10.7–68.8	45	223.2	146.1–264.6
Sputum IL-8, pg/mL	70	3,125	1,935–3,698	35	1,946	1,574–2,267	35	3,682	3,420–4,640
Neutrophils†	45	1.82	0.88–3.79	22	0.88	0.58–1.15	23	3.67	2.32–7.92
Eosinophils‡	45	25	7–85	22	7	3.5–16.5	22	85	40.3–326
Bacteria (log)§	77	7.7	7.0–8.25	37	7.00	6.00–7.30	40	8.1	7.9–8.8

^*Biomarker data refer to samples collected during stable disease (exacerbation free).

^†Sputum neutrophil count × 10⁶ per gram of sputum.

^‡Sputum eosinophil count × 10³ per gram of sputum.

^§Bacteria (log) = log₁₀ (total airway lower airway bacterial load).