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editorial
. 2011 Mar 17;30(4):361–374. doi: 10.1016/j.healun.2011.01.701

Table 3a.

Respiratory Viral Infection in CTTX

Infection Signs/symptoms Radiology Virology
Respiratory viral infections (RVIs)
 Asymptomatic RVI None No changes Recovery of virus from nasopharynx or bronchoalveolar lavagea
 Clinical RVI

  • Two or more of the following:

  •  • Fever >38oC

  •  • Rhinorrhea

  •  • Nasal congestion

  •  • Sore throat

  •  • Sneezing

  •  • Chills/rigors

  •  • Myalgia

  •  • Headache

  • AND exclusion of other etiology for symptoms including but not limited to recovery of another pathogen or histopathology for acute rejection

 Chest radiograph or CT scan not performed Lack of confirmatory testing for respiratory viral pathogen (not performed or negative assay)
 Upper respiratory tract infection As for clinical RVI No evidence of lower respiratory tract Infection Confirmation of a respiratory viral pathogen
 Lower respiratory tract infection

  • Clinical symptoms (two or more of those listed above for URI) PLUSone or more of the following symptoms of lower respiratory tract involvement:

  •  • Cough

  •  • Dyspnea

  • Physical findings (one or more of the following):

  •  • Hypoxia (new onset or increasing)

  •  • New or increased O2 requirement

  •  • New crackles, rales or wheezing

  • Acute respiratory distress syndrome

 New/worsening radiographic changes on chest X-ray or CT scan Confirmation of a respiratory viral pathogen OR histopathologic evidence AND exclusion of AR
a

Respiratory viral infection diagnostic tools: nucleic acid amplification (including PCR methods); tissue (cell) culture, both conventional and rapid; culture (shell-vial/R-mix); indirect and direct immunofluorescence antibody (IFA/DFA) tests; and enzyme immunoassays (EIAs).