Table 2.
Measurement of association and dissociation rate constants and affinities of scFvs anti-hCD13-1 and -3 by surface plasmon resonance
| scFv | ka (M−1 s−1) | kd (s−1) | KD (M) |
|---|---|---|---|
| ×105 | ×10−4 | ×10−10 | |
| CD13-1 | 4.42 | 3.13 | 7.27±1.75 |
| CD13-3 | 1.71 | 5.51 | 32.9±6.6 |
Measurement of association and dissociation rate constants and affinities of scFvs anti-hCD13-1 and -3 by surface plasmon resonance
| scFv | ka (M−1 s−1) | kd (s−1) | KD (M) |
|---|---|---|---|
| ×105 | ×10−4 | ×10−10 | |
| CD13-1 | 4.42 | 3.13 | 7.27±1.75 |
| CD13-3 | 1.71 | 5.51 | 32.9±6.6 |