Table 1.
Genes showing significantly differential expressions between dexamethasone-treated and sham-treated cells
| Primary B cells | Lymphoblastoid cell lines | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Increased expression | Decreased expression | Increased expression | Decreased expression | ||||||||
| Gene | Log2FC | Q value (%) | Gene | Log2FC | Q value (%) | Gene | Log2FC | Q value (%) | Gene | Log2FC | Q value (%) |
| TSC22D3 | 1.183 | 0 | LTA | −1.105 | 0 | TSC22D3 | 1.186 | 0 | LTA | −1.115 | 0 |
| SAP30 | 1.132 | 0 | EGR2 | −1.072 | 0 | SAP30 | 1.172 | 0 | PEA15 | −1.08 | 0 |
| DDIT4 | 1.128 | 0 | LYSMD2 | −1.068 | 0 | DDIT4 | 1.128 | 0 | PRMT1 | −1.069 | 0 |
| FKBP5 | 1.118 | 0 | PEA15 | −1.056 | 0 | TXNIP | 1.112 | 0 | SAMSN1 | −1.068 | 0 |
| SMAP2 | 1.107 | 0 | HMOX1 | −1.073 | 3.39 | FKBP5 | 1.102 | 0 | CD83 | −1.054 | 0 |
| CCND3 | 1.092 | 0 | LPXN | −1.058 | 4.82 | SMIM3 | 1.101 | 0 | SLAMF7 | −1.053 | 0 |
| BLK | 1.08 | 0 | BCL2A1 | −1.042 | 4.82 | PSCDBP | 1.09 | 0 | NUS1P1 | −1.05 | 0 |
| SMIM3 | 1.067 | 0 | CSK | −1.041 | 4.82 | CASP6 | 1.082 | 0 | LPXN | −1.043 | 0 |
| SOCS1 | 1.063 | 0 | CYBASC3 | −1.032 | 4.82 | CLIP1 | 1.08 | 0 | P2RY10 | −1.042 | 0 |
| CNDP2 | 1.06 | 0 | P4HA1 | 1.08 | 0 | PRDX1 | −1.038 | 0 | |||
| H1FX | 1.054 | 0 | TOX2 | 1.077 | 0 | OBFC2A | −1.034 | 0 | |||
| CASP6 | 1.051 | 0 | SMAP2 | 1.076 | 0 | TRAF1 | −1.029 | 0 | |||
| TIPARP | 1.049 | 0 | SLC16A3 | 1.063 | 0 | NHP2 | −1.028 | 0 | |||
| P4HA1 | 1.045 | 0 | CDCP1 | 1.06 | 0 | PLEK | −1.081 | 1.5 | |||
| VIL2 | 1.044 | 0 | CNDP2 | 1.059 | 0 | GAR1 | −1.054 | 1.5 | |||
| TXNIP | 1.145 | 3.19 | BIN1 | 1.058 | 0 | CSK | −1.053 | 1.5 | |||
| DUSP1 | 1.099 | 3.19 | S100A10 | 1.055 | 0 | DDX21 | −1.043 | 1.5 | |||
| BTG1 | 1.065 | 3.19 | CCDC6 | 1.055 | 0 | BCL2A1 | −1.058 | 3.24 | |||
| THOP1 | 1.059 | 3.19 | CCND3 | 1.052 | 0 | CD40 | −1.056 | 3.24 | |||
| TOX2 | 1.058 | 3.19 | AP3S1 | 1.05 | 0 | EGR2 | −1.054 | 3.24 | |||
| SEMA4D | 1.055 | 3.19 | THOP1 | 1.049 | 0 | MS4A1 | −1.047 | 3.24 | |||
| DSTN | 1.054 | 3.19 | FGD2 | 1.049 | 0 | HSPD1P4 | −1.045 | 3.24 | |||
| ETS1 | 1.053 | 3.19 | BTLA | 1.049 | 0 | LOC148430 | −1.044 | 3.24 | |||
| MXD4 | 1.051 | 3.19 | AIDA | 1.043 | 0 | NOP16 | −1.04 | 3.24 | |||
| SORT1 | 1.047 | 3.19 | HOST2 | 1.043 | 0 | TIMM23 | −1.03 | 3.24 | |||
| CSDA | 1.046 | 3.19 | STRBP | 1.04 | 0 | PRELID1 | −1.029 | 3.24 | |||
| PLP2 | 1.038 | 3.19 | PTPN1 | 1.039 | 0 | APEX1 | −1.028 | 3.24 | |||
| IQGAP2 | 1.037 | 3.19 | IQGAP2 | 1.037 | 0 | HMOX1 | −1.111 | 4.18 | |||
| KLF2 | 1.059 | 4.82 | CCDC102A | 1.035 | 0 | DNAJA1 | −1.073 | 4.18 | |||
| BIN1 | 1.046 | 4.82 | COQ8A | 1.031 | 0 | LYSMD2 | −1.067 | 4.18 | |||
| CDCP1 | 1.04 | 4.82 | FOXN3 | 1.027 | 0 | ACADM | −1.058 | 4.18 | |||
| CHSY1 | 1.035 | 4.82 | SYCP3 | 1.069 | 1.26 | SPIB | −1.052 | 4.18 | |||
| MAP2K1 | 1.034 | 4.82 | DSTN | 1.066 | 1.26 | HSP90AB1 | −1.052 | 4.18 | |||
| SORT1 | 1.066 | 1.26 | TLR7 | −1.048 | 4.18 | ||||||
| CHPT1 | 1.065 | 1.26 | GADD45B | −1.047 | 4.18 | ||||||
| HACD2 | 1.062 | 1.26 | ADO | −1.045 | 4.18 | ||||||
| EZR | 1.056 | 1.26 | MTX2 | −1.043 | 4.18 | ||||||
| STUM | 1.052 | 1.26 | DYNLL1 | −1.04 | 4.18 | ||||||
| RASSF2 | 1.051 | 1.26 | AGPAT5 | −1.039 | 4.18 | ||||||
| KLF2 | 1.042 | 1.26 | SQSTM1 | −1.038 | 4.18 | ||||||
| INIP | 1.037 | 1.26 | POLR1C | −1.037 | 4.18 | ||||||
| CFLAR | 1.035 | 1.26 | DKC1 | −1.036 | 4.18 | ||||||
| TMEM243 | 1.034 | 1.26 | HSPD1 | −1.035 | 4.18 | ||||||
| VKORC1 | 1.024 | 1.26 | IFIH1 | −1.035 | 4.18 | ||||||
| TIPARP | 1.076 | 3.24 | HVCN1 | −1.034 | 4.18 | ||||||
| VAMP5 | 1.064 | 3.24 | ZNF267 | −1.031 | 4.18 | ||||||
| SLC44A2 | 1.056 | 3.24 | YRDC | −1.03 | 4.18 | ||||||
| RASSF4 | 1.039 | 3.24 | ADAR | −1.029 | 4.18 | ||||||
| SLC15A4 | 1.046 | 4.18 | SMARCC1 | −1.024 | 4.18 | ||||||
| MCUB | 1.045 | 4.18 | |||||||||
FC, fold change. Bold denotes the common genes showing significantly differential expressions between dexamethasone- and sham-treated cells in both primary B cells and lymphoblastoid cell lines