Fig. 3.

Engineering of infectious clones in N gene. (A) Schematic presentation of the nucleocapsid (N) protein. NLS and RBD overlap each other. (B) Deletion tolerance regions (yellow) in N protein. NLS, nuclear localization signal; NES, nuclear export signal; P, phosphorylation site; S, disulfide bridge, RBD, RNA-binding domain; NoLS, nucleolar localization signal. NCI, non-covalent interaction motif. Numbers indicate amino acid positions of N. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)