Table 3.
Antibody titers in sera of chickens following immunization with recombinant fowlpox virus co-expressing the infectious bronchitis virus (IBV) S1 gene and the chicken interferon-γ gene.
| Group | Time (weeks) |
|||||||
|---|---|---|---|---|---|---|---|---|
| 0a | 1 | 2 | 3b | 4 | 5 | 6 | ||
| LX4 | Vaccine | 0 | 1145c | 1731 | 1608 | 2418 | 6393 | 5948 |
| Controld | 0 | 0 | 0 | 135 | 2290 | 4984 | 4039 | |
| LHLJ04XI | Vaccine | 0 | 1145 | 1731 | 1608 | 2250 | 5805 | 5425 |
| Control | 0 | 0 | 0 | 135 | 2462 | 4014 | 4584 | |
| LHB | Vaccine | 0 | 1145 | 1731 | 1608 | 2044 | 9799 | 4685 |
| Control | 0 | 0 | 0 | 135 | 2348 | 3849 | 6088 | |
| LSC99I | Vaccine | 0 | 0 | 0 | 135 | 2602 | 6835 | 4396 |
| Control | 0 | 1145 | 1731 | 1608 | 1433 | 3748 | 3796 | |
| LTJ95I | Vaccine | 0 | 1145 | 1731 | 1608 | 1823 | 3883 | 3198 |
| Control | 0 | 0 | 0 | 135 | 1847 | 4614 | 3519 | |
Values are antibody mean ± S.E.M.
a
Chickens (n = 12 per group) were immunized with recombinant fowlpox virus co-expressing the infectious bronchitis virus (IBV) S1 gene and the chicken interferon-γ gene at week 0.
b
Chickens (n = 12 per group) were challenged with 0.2 mL of allantoic fluid containing 10,000 EID50 of IBV strains LX4, LHLJ04XI, LHB, LSC99I and LTJ95I at week 3 post-vaccination.
c
Chicken sera were collected at weeks 0, 1, 2, 3, 4, 5 and 6.
d
Control chickens received PBS (n = 12 per group).