Table 2.
Examples of promising candidate antiviral agents currently in late stage development.
| Antiviral agent | Target | Mechanism | Developmental stage | Reference |
|---|---|---|---|---|
| Nitazoxanide | Influenza | Multiple | Phase 2/3 | 100 |
| Favipiravir (T-705) | Influenza and other viruses | Inhibition of RNA polymerase | Phase 3 | 101 |
| Anti-M2e monoclonal antibodies | Influenza | Binding to M2e epitope | Phase 2 | 102 |
| GS-5806 | RSV | Fusion inhibitor | Phase 2 | 105 |
| Vapendavir (BTA798) | Rhinovirus | Capsid binder | Phase 2 | 109 |
| Inhaled beta-interferon | Rhinovirus and other viruses | Restored antiviral response in asthmatics | Phase 2/3 | 110 |