Table 3.

Correlation between IFN lambda 1–3 subtypes and host and virological parameters in infants suffering from RSV or HRV associated bronchiolitis.

Host and virological parameters	RSV		RSV		HRV		HRV
	IFN lambda 1		IFN lambda 2–3		IFN lambda 1		IFN lambda 2–3
	p	r	p	r	p	r	p	r
Age (days)	0.476	0.115	0.444	0.138	0.121	−0.340	0.131	−0.359
Birth Weight (kg)	0.061	0.295	0.05	0.394	0.905	0.027	0.991	0.003
Weight on admission (kg)	0.484	0.121	0.475	0.080	0.710	−0.083	0.811	−0.161
Neutrophils (cells/μl)	0.394	0.138	0.597	0.097	0.640	−0.106	0.983	−0.005
Lymphocytes (cells/μl)	0.759	−0.050	0.122	−0.279	0.743	0.074	0.764	−0.074
Eosinophils (cells/μl)	0.525	−0.103	0.394	−0.156	0.954	−0.013	0.197	−0.310
Platelets (cells/μl)	0.515	0.106	0.694	−0.072	0.440	−0.173	0.557	−0.144
Glycemia (mg/dl)	0.788	0.045	0.157	0.256	0.259	−0.251	0.303	−0.249
Sodium (mEq/l)	0.212	−0.204	0.279	−0.201	0.286	0.248	0.619	−0.066
C-reactive protein (mg/dl)	0.387	−0.142	0.707	−0.070	0.715	−0.083	0.895	0.010
Hemoglobin (g/dl)	0.811	0.039	0.558	−0.108	0.601	0.118	0.764	−0.166
Clinical Score index	0.025	0.350	0.204	0.227	0.308	0.228	0.352	0.226
Days in hospital (days)	0.832	−0.034	0.352	0.167	0.345	0.211	0.988	−0.004
Viral load (number of copies/ml)	0.800	0.041	0.723	0.064	0.697	−0.090	0.918	0.028

Spearman's rho coefficient was calculated in order to assess the correlation between IFN lambda 1–3 mRNA levels and host and virological parameters. Significant correlations are highlighted in bold-face. Analysis was performed with SPSS v.17.0 for Windows. * The clinical severity was assigned to each infant with the range 0–8, based on respiratory rate (<45 breaths/m = 0, 45–60 breaths/m = 1, >60 breaths/m = 2), arterial oxygen saturation in room air (>95% = 0, 95–90% = 1, <90% = 2), presence of retractions (none = 0, present = 1, present + nasal fare = 2), and ability to feed (normal = 0, reduced = 1, endovenous = 2).