Table 1.
Predicted pI values of Ad major capsid proteins
| Tropism | Serotype | Hexon | Penton base | Fiber (head) | Subgenus | Receptor used |
|---|---|---|---|---|---|---|
| Enteric | Ad41,Long | 5.49 | 5.75 | 7.51 (8.64) | F | CAR |
| Short | 9.13 (7.24) | Not CAR | ||||
| Ad40,Long | 6.68 | 5.75 | 7.51 | F | CAR | |
| Short | 7.78 | Not CAR | ||||
| Respiratory | Ad2 | 4.86 | 5.05 | 5.85 (6.35) | C | CAR |
| Ad5 | 5.03 | 5.18 | 5.89 (5.91) | C | CAR | |
| Ad4 | 4.58 | n.d. | 5.25 | E | CAR | |
| Urinary | Ad35 | 5.10 | 5.32 | 4.71 | B | Not CAR |
| Respiratory and ocular | Ad3 | 5.32 | 5.26 | 5.61 | B | Not CAR |
| Enteric | Ad31 | 5.25 | n.d. | 6.11 | A | CAR |
| (c.d.?) | Ad12 | 5.55 | 6.20 | 4.60 | A | CAR |
| Ocular and urogenital | Ad37 | n.d. | 8.76 | 9.56 (9.28) | D | Sialic acid (Not CAR) |
| Ocular |
Ad8 | 5.50 | 5.39 | 9.42 | D | Not CAR |
| Ad30 | n.d. | n.d. | 5.16 | D | Not CAR | |
| Ad9 | 4.72 | n.d. | 5.70 | D | CAR | |
| Ad15 |
4.76 |
n.d. |
5.71 |
D |
CAR |
c.d.?: suggested involvement in coeliac disease (Kagnoff et al., 1987). n.d.: sequence not known. Accession numbers to the sequences used for the calculation of predicted pI values are given in Table 2 (see Materials and methods).