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. 2014 Sep 28;32(48):6485–6492. doi: 10.1016/j.vaccine.2014.09.030

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© 2014 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 5 — RSV-B 18537 viral titer in lung and nasal tissue from post challenge cotton rats. Female cotton rats, 4–6 weeks old were immunized by intramuscular injection with adjuvanted RSV F nanoparticle vaccine or palivizumab. Animals in the placebo group received PBS. All animals were challenged with RSV-B 18537 on day 42 and sacrificed on day 46. Viral titer is represented in Panel A. RSV-B 18537 log₁₀ pfu/g lung tissue, and Panel B. RSV-B 18537 log₁₀ pfu/g nasal tissue. GMT for each group shown as the bar and *p < 0.01 compared to 3 μg RSV F group, ⁺p < 0.05 compared to 0.3 μg RSV F group. LOD is the lower limit of detection. The limit of detection of this assay was 2.0 log₁₀.