Table 2.

Amino acids differences between different reovirus type 3 Dearing.

	T3DKa	T3DSb	T3DWc	T3DHd	Reolysine	Amino acid position
λ3	M				L	979
	S				R	1045
	N	S	S		S	1048
	S		P			1186
λ2	G	E	E		E	504
	G				R	509
	I		M	M		1165
λ1	A		T			201
	I	S	S		S	500
	A		T			574
	Q				H	852
	M		V			982
	G		D			1017
μ2	A			V		122
	S	P	P		P	208
	R	Q	Q	Q	Q	342
	A				S	528
μ1	E				D	73
	T			I		142
	A	V	V			305
	–		R	R		439
	A		V	V		440
	Q		M	M		441
	A	T				449
	A		T			529
μNS	K	E	E		E	180
	A	V			V	705
	G				D	707
σ1	V				A	22
	T	I				249
	Y	S				253
	T	A	A		A	408
σ3	W				R	133
	G				K	198
	E		D	D	D	229

^aT3D-Kobayashi, wild-type virus from the reverse genetics system (Kobayashi et al., 2007).

^bT3D-Sandekian, original wild-type virus reported in this study

^cT3D-Wollenberg, wild-type virus (R124) used in van den Wollenberg et al. (2012).

^dT3D-Hosseini, wild-type unpublished virus sequence from NCBI database.

^eT3D-Reolysin^®, wild-type virus used in clinical trials as described in Chakrabarty et al. (2014).