Figure 3.

Moderate Derangement of Circulating Immunoglobulins in Pneumonia Caused by SARS-CoV-2

Serum amounts of IgG subclasses (A–D), IgM (E), and IgA (F) of patients with CAP caused by SARS-CoV-2 are shown. Patients are classified into three states of immune activation: intermediate, dysregulation, and MAS. Findings are compared with those in patients with bacterial CAP, who are classified into three states of immune activation: intermediate, immunoparalysis, and MAS.

Bars in each graphic represent mean values and standard errors. Only statistically significant comparisons are indicated by the arrows; ^∗p < 0.05; ^∗∗p < 0.0001; ^∗∗∗p < 0.0001. Comparisons were done by the Mann-Whitney U test followed by correction for multiple comparisons.