Table 3.
Characteristics of children with HRSV infections while on palivizumab
| Patient | Visit | Age (months) | Date of NPA | # Doses before NPA | Time since last dose (days) | Age at birth (weeks) | Diagnosis | Hospitalization (days) | Cult. | RT-PCR (type) | Amino acid change (F gene) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 002 | 6 | 6 | 01-26-2005 | 4 | 15 | 31.6 | Bronchiolitis | No | − | +(B) | – |
| 002 | 7 | 6 | 01-31-2005 | 4 | 20 | 31.6 | Bronchiolitis | No | − | +(B) | – |
| 010 | 3 | 6 | 02-04-2005 | 4 | 24 | 31.7 | Bronchiolitis | No | + | +(A) | – |
| 022 | 1 | 6 | 03-16-2005 | 6 | 8 | 33.1 | URTI | No | − | +(A) | 410(L/V), 422(C/G), 485(S/F) |
| 029 | 1 | 10 | 04-05-2005 | 6 | 28 | 30.3 | Bronchiolitis | No | + | −(A)a | –a |
| 038 | 1 | 7 | 04-21-2005 | 7 | 8 | 32.7 | Bronchiolitis, AOM | No | − | +(B) | 272(K/E) |
| 045 | 3 | 8 | 03-11-2005 | 5 | 23 | 25.0 | Croup | No | + | +(B) | – |
| 052 | 1 | 11 | 04-13-2005 | 6 | 28 | 26.4 | URTI | No | + | +(B) | – |
| 058 | 4 | 6 | 04-19-2005 | 7 | 6 | 32.9 | Bronchiolitis | No | + | +(B) | 107(A/V) |
| 062 | 2 | 3 | 02-18-2005 | 4 | 10 | 33.4 | Bronchiolitis | Yes (7) | + | +(A) | 183(N/D) |
| 067 | 1 | 7 | 02-18-2005 | 4 | 10 | 33.7 | Bronchiolitis | No | − | +(A) | – |
Note: URTI: upper respiratory tract infection; AOM: acute otitis media; NPA: nasopharyngeal aspirate.
a
Genotype and F sequence determined from viral isolate since RT-PCR on clinical sample was negative.