Table 2.

Local and systemic solicited adverse events

	Low-dose group (n=6)			Intermediate-dose group (n=9)			High-dose group (n=9)
	Mild	Moderate	Severe	Mild	Moderate	Severe	Mild	Moderate	Severe
Any symptom	5 (83%)	1 (17%)	0	5 (56%)	2 (22%)	0	0	8 (89%)	1 (11%)
Any local symptom	4 (67%)	0	0	7 (78%)	0	0	5 (56%)	4 (44%)	0
Injection site pain	2 (33%)	0	0	7 (78%)	0	0	5 (56%)	4 (44%)	0
Pruritus	2 (33%)	0	0	1 (11%)	0	0	2 (22%)	0	0
Warmth	1 (17%)	0	0	1 (11%)	0	0	2 (22%)	0	0
Swelling	0	0	0	0	0	0	0	0	0
Erythema	2 (33%)	0	0	1 (11%)	0	0	2 (22%)	0	0
Any systemic symptom	5 (83%)	1 (17%)	0	5 (56%)	2 (22%)	0	1 (11%)	7 (78%)	1 (11%)
Fever	0	0	0	1 (11%)	0	0	1 (11%)	3 (33%)	1 (11%)
Feverishness	1 (17%)	0	0	4 (44%)	0	0	4 (44%)	3 (33%)	0
Arthralgia	1 (17%)	0	0	2 (22%)	0	0	5 (56%)	0	0
Myalgia	2 (33%)	0	0	4 (44%)	0	0	5 (56%)	2 (22%)	0
Headache	3 (50%)	1 (17%)	0	5 (56%)	0	0	2 (22%)	5 (56%)	0
Fatigue	4 (67%)	0	0	5 (56%)	1 (11%)	0	3 (33%)	4 (44%)	0
Nausea	0	0	0	2 (22%)	1 (11%)	0	4 (44%)	1 (11%)	0
Malaise	1 (17%)	0	0	4 (44%)	1 (11%)	0	1 (11%)	5 (56%)	0