Table 2.

Haematological changes

		Low-dose group (n=14)		High-dose group (n=12)
		Geometric mean per nL (95% CI)	p value	Geometric mean per nL (95% CI)	p value
Thrombocytes		..	0·048	..	0·0005
	Day −1	257 (236–280)	..	273 (237–315)	..
	Day 1	241 (214–272)	..	216 (186–251)	..
White blood cells		..	0·041	..	0·0010
	Day −1	7·0 (5·9–7·6)	..	7·1 (6·2–8·1)	..
	Day 3	5·6 (4·9–6·4)	..	4·6 (4·0–5·4)	..
Neutrophils		..	0·080	..	0·0010
	Day −1	4·0 (3·5–4·6)	..	4·5 (3·8–5·3)	..
	Day 3	3·2 (2·8–3·7)	..	2·2 (1·8–2·7)	..
Lymphocytes		..	0·0052	..	0·0005
	Day −1	1·8 (1·4–2·3)	..	1·9 (1·5–2·3)	..
	Day 1	1·3 (1·1–1·6)	..	0·9 (0·8–1·1)	..

Depicted p values were calculated using Wilcoxon signed-rank test. p values were not adjusted for multiple comparisons.