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Cellular protein inhibitors and immuno-stimulators from (65) to (72). Tertiary structure of host protein cyclophilin A in complex with phenyl–pyrrolidine 31 is visualized (PDB code: 3RDD). In addition, cyclophilin A inhibitors include alisporivir, bis-amide derivative 25, and NIM258 (Table 20). Other compounds target other host proteins to offer antiviral activity (see details in Section 5).
