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. 2017 Feb 24;142:83–122. doi: 10.1016/j.antiviral.2017.02.014

Table 15.

Efficacy of 12.5 mg ombitasvir + 75 mg paritaprevir + 50 mg ritonavir fixed-dose two pills QD plus 250 mg dasabuvir BID plus ribavirin for 24w.

Cirrhosis Prior treatment SVR12 rate in GT-1 Study and trial phase Ref.
Cirrhosis Naïve 1a: 92.9% (52/56), 1b:100% (18/18) TURQUOISE-II, phase 3 Poordad et al., 2014
Null response to PegIFNα/RBV 1a:92.9% (39/42), 1b:100% (20/20)
Partial response to PegIFNα/RBV 1a: 100% (10/10), 1b:100% (3/3)
Relapse to PegIFNα/RBV 1a: 100% (13/13), 1b:100% (10/10)
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