Table I.
Demographic data at baseline and during infection
Subjects | N | Sex (M/F) | Age (y)∗ | Smoking (pack-years)∗ | FEV1 (% of predicted)∗ |
FEV1/FVC (%)∗ |
Peak sputum virus load (log10 copies/mL) | ||
---|---|---|---|---|---|---|---|---|---|
Baseline | Day 9 | Baseline | Day 9 | ||||||
Nonsmoker | 11 | 4/7 | 62 ± 5.1† | 0 ± 0 | 101 ± 11.8 | 89 ± 10.8 | 78 ± 3.7 | 87 ± 9.0 | 7 ± 2.4 |
Smoker | 20 | 10/10 | 51 ± 7.1 | 34 ± 10.5 | 104 ± 14.5 | 89 ± 26.1 | 79 ± 5.7 | 73 ± 9.0 | 6 ± 3.6 |
COPD | 17 | 12/5 | 61 ± 8.1† | 46 ± 21.0‡ | 68 ± 5.1§ | 58 ± 11.7§ | 57 ± 8.1§ | 54 ± 10.1§ | 8 ± 3.9 |
FVC, Forced vital capacity.
Results are expressed as mean ± SD.
P = .0003 vs smokers (Student t test).
P = .025 vs smokers (Student t test).
P < .0001 vs nonsmokers and smokers.