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. 2008 Aug 1;26(39):4991–4997. doi: 10.1016/j.vaccine.2008.07.029

Table 2.

Lymphocyte phenotypes in peripheral blood mononuclear cells of dogs with visceral leishmaniasis subjected to immunotherapy with Leishmune®

Treatment Dog CD4% CD8% CD21%
Leishmune® 1 38.81 32.52 4.59
2 55.65 31.26 18.85
3 32.78 21.10 11.69
4 50.13 19.16 18.54
5 20.35 53.79 17.37
6 33.10 22.28 13.42
7 48.61 23.59 17.25
8 23.29 52.99 9.70
9 40.13 17.42 4.01
10 35.68 56.24 3.45
11 54.86 19.24 4.27
12 40.03 16.61 9.46
13 85.37 12.63 9.81
14 80.47 12.19 3.06
15 29.83 9.28 12.51
Average 44.61 26.69 10.53
IC95% 34.79–54.41 18.48–34.87 7.52–13.54



Normal 1 36.09 20.85 4.35
2 43.59 25.90 5.58
3 37.07 16.08 6.37
4 47.94 17.10 3.33
5 35.17 16.48 9.43
6 23.68 24.75 0
7 41.71 33.46 5.46
8 36.07 25.44 0.44
9 35.38 14.89 4.6
Average 44.07 19.45 6.07
IC95% 21.40–51.28 11.27–22.50 3.01–7.98

Data of Leishmune®-vaccinated dogs of Araçatuba and Andradina, 2 years after vaccination and of healthy normal dogs.