Table 1.

Available cell lines and cell models of the animal and human gut.

Cell line/model	Cell origin	Type	Status	Species	References	Supplier
Caco-2	Colon adenocarcinoma	Epithelia	Cancerogenic	Human	(Cui et al., 2009, Jalal et al., 1992, Lee et al., 2009, Schnabl et al., 2009, Uchida et al., 2009, Visco et al., 2009)	ATCC
HT-29	Colon adenocarcinoma	Epithelia	Cancerogenic	Human	(Chen et al., 1987, Didier et al., 1996, Takahashi et al., 1996)	ATCC
Intestine 407	Small intestine /HeLa	Epithelia	Cancerogenic	Human	(Henle and Deinhardt, 1957, Lavappa et al., 1976)	ATCC
HIEC-6	Small intestine	Epithelia	Normal	Human	(Beaulieu, 1997, Beaulieu, 1999, Belanger and Beaulieu, 2000, Lussier et al., 2000)	University of Sherbrooke (Beaulieu, J.F.)
H4	Small intestinal foetal tissue	Epithelia	Normal	Human	(Claud et al., 2003, Lu et al., 2008, Lu et al., 2009, Nanthakumar et al., 2000)	Massachusetts General Hospital (Walker, W.A.)
H4-1	Small intestinal foetal tissue	Epithelia	Normal	Human	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
CaSki	Small intestine metastatic cervical cancer	Epithelia	Cancerogenic	Human	(Baker et al., 1987, Hussa et al., 1986, Pattillo et al., 1977)	ATCC
IEC-6	Small intestine	Epithelia	Normal	Rat	(Quaroni and Isselbacher, 1981, Quaroni et al., 1978)	ATCC
IEC-18	Smal intestine	Epithelia	Normal	Rat	(Quaroni and Isselbacher, 1981, Quaroni et al., 1978)	ATCC
IPEC-J2	Small intestine of neonatal pig	Epithelia	Normal	Pig	(Berschneider, 1989, Schierack et al., 2006)	Freie Universitaet Berlin (Wieler, L.H.)
IPEC-J2-3	Small intestine of neonatal pig	Epithelia	Normal	Pig	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
IPEC-J2-9	Small intestine of neonatal pig	Epithelia	Normal	Pig	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
PSI-1	Mature small intestine	Epithelia	Normal	Pig	(Cencic et al., 2008a, Cencic et al., 2008b, Gradisnik et al., 2006)	BioNutriTech
CLAB	Enterocytes	Epithelia	Normal	Pig	(Cencic et al., 2008a, Cencic et al., 2008b, Gradisnik et al., 2006)	BioNutriTech
CIEB	Small intestinal	Epithelia	Normal	Calf	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
GIE	Small intestinal	Epithelia	Normal	Goat	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
OSI	Small intestinal	Epithelia	Normal	Sheep	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
B1oxi	Small intestinal	Epithelia	Normal	Chicken	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
B5	Small intestinal	Epithelia	Normal	Chicken	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
B6	Small intestinal	Epithelia	Normal	Chicken	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Pom2	Blood	Monocytes/macrophages	Normal	Pig	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
BOMA	Blood	Monocytes/macrophages	Normal	Calf	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
MOLT-4	Blood	Monocytes/macrophages	Normal	Sheep	Olivier et al. (2001)	INRA, Tours
GOMA	Blood	Monocytes/macrophages	Normal	Goat	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
COMA	Blood	Monocytes/macrophages	Normal	Chicken	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
TLT	Blood	Monocytes/macrophages	Normal	Human	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Human	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Pig	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Calf	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Goat	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Sheep	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Chicken	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech
Gut 3D model		Functional	Normal	Horse	(Cencic et al., 2006, Cencic et al., 2007a, Cencic et al., 2007b, Cencic et al., 2008a, Cencic et al., 2008b, Cencic et al., 2009)	BioNutriTech