Table 3.
Multiple linear regression of mean difference in lower airway %neutrophils according to infective status on NPA and BAL.
| Unadjusteda mean difference in neutr% (IQR) | p-Value | Adjustedb mean difference in neutr% (IQR) | p-Valuec | Betad | |
|---|---|---|---|---|---|
| NPA | |||||
| HAdV | 20 (3, 37) | 0.020 | 18 (1, 35) | 0.042 | 0.245 |
| HRV | 5 (−9, 19) | 0.486 | −2 (−16, 12) | 0.782 | −0.033 |
| Bacteria ≥ 105 cfu/ml (on BAL) | 16 (3, 30) | 0.016 | 15 (1, 28) | 0.035 | 0.256 |
| BAL | |||||
| HAdV | 15 (−3, 32) | 0.097 | 18 (0.3, 35) | 0.046 | 0.235 |
| HRV | 4 (−10, 19) | 0.550 | 0 (−14, 15) | 0.950 | 0.007 |
| Bacteria ≥ 105 cfu/ml (on BAL) | 16 (3, 30) | 0.016 | 18 (4, 31) | 0.01 | 0.311 |
a
Unadjusted mean difference in %neutrophils between HAdV, HRV and bacteria positive and negative groups calculated using independent samples t-test.
b
Adjusted mean difference in %neutrophils using multiple linear regression (adjusted for viral co-detection and bacterial infection).
c
p-Values remain significant after logarithmic transformation of %neutrophils therefore mean differences reported.
d
Standardized coefficient indicates independent influence of variable on %neutrophils.