Table 2.
Association of XPO1 Overexpression and NF-κB with Clinicopathological Features and Ki67 Expression
| Clinicopathological | Patients | XPO1 expression |
P-value | NF-κB expression |
P-value | ||
|---|---|---|---|---|---|---|---|
| features and Ki67 expression | No (%) | Nonoverex-pressio | Overexpr-ession | -ve | +ve | ||
| Tumor differentiation | 0.059 | 0.906 | |||||
| Well | 19 (47.5) | 12 | 7 | 13 | 6 | ||
| Moderate/Poor | 21 (52.5) | 7 | 14 | 14 | 7 | ||
| Lymph node metastasis | 0.366 | 0.027* | |||||
| Negative | 16 (40) | 9 | 7 | 14 | 2 | ||
| Positive | 24 (60) | 10 | 14 | 13 | 11 | ||
| Tumor stage | 0.049* | 0.286 | |||||
| I–II | 11 (27.5) | 8 | 3 | 4 | 7 | ||
| III-IV | 29 (72.5) | 11 | 18 | 7 | 22 | ||
| Ki67 | 0.001** | 0.007** | |||||
| <40% | 11 (27.5) | 10 | 1 | 11 | 0 | ||
| ≥40% | 29 (72.5) | 9 | 20 | 16 | 13 | ||
*,** represent the statistical P<0.001 and P<0.0001, respectively.