Table 5.
Kaplan Meier Analysis of Clinicopathological Characteristics and c-Myc Nuclear Expression for Overall Survival (OS) 52 Patients and Disease Free Survival (DFS) of 48 Patients with MIUC of the Bladder
| Parameter | OS |
DFS |
|---|---|---|
| p value* | p value* | |
| Gender | 0.761 | 0.738 |
| Males | ||
| Females | ||
| Variant of UC | 0.409 | 0.449 |
| Conventional | ||
| Sarcomatoid | ||
| Differentiation of UC** | 0.453 | 0.367 |
| Squamous | ||
| Absent | ||
| Pattern of tumor invasion | ||
| Nodular pattern | 0.463 | 0.644 |
| Present | ||
| Absent | ||
| Trabecular pattern | 0.695 | 0.837 |
| Present | ||
| Absent | ||
| Infiltrative pattern | 0.158 | 0.223 |
| Present | ||
| Absent | ||
| Bilharziasis | 0.285 | 0.270 |
| Present | ||
| Absent | ||
| Necrosis | 0.509 | 0.194 |
| Present | ||
| Absent | ||
| PNI | 0.624 | 0.766 |
| Present | ||
| Absent | ||
| LVI | 0.060 | 0.548 |
| Present | ||
| Absent | ||
| pT stage | 0.050 | 0.449 |
| T2a | ||
| T2b | ||
| T3a | ||
| T3b | ||
| T4a | ||
| pN stage | 0.050 | 0.633 |
| N0 | ||
| N1 | ||
| N2 | ||
| M stage | 0.011 | Not Done *** |
| M0 | ||
| M1b | ||
| Stage grouping | 0.018 | 0.800 **** |
| II | ||
| Stage grouping | 0.018 | 0.800 **** |
| IIIA | ||
| IIIB | ||
| IVB | ||
| c-Myc nuclear expression | 0.161 | 0.272 |
| High (>120) | ||
| Low (≤120) |
LVI, lymphovascular invasion; PNI, perineural invasion; UC, urothelial carcinoma; * p value by Log Rank test; ** Glandular group was excluded from analysis as they were only 2 cases; *** Not Done as the patients with M1b stage developed metastasis at the time of operation (i.e. had no disease free survival period), so no comparison analysis could be performed; **** Comparison was done between stages II, IIIA and IIIB. IVB did not included.