Table 4.23.
Kaplan–Meier estimates of the age of patients at the time when irreversible disability scores of DSS 4, DSS 6 and DSS 7 were obtained in 1844 patients with multiple sclerosis.a
| Age at assignment of a score of DSS 4 |
Age at assignment of a score of DSS 6 |
Age at assignment of a score of DSS 7 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | No. of patients (n = 1844) | Median (years) | (95% CI) | p valueb | Median (years) | (95% CI) | p valueb | Median (years) | (95% CI) | p valueb |
| Overall | 1844 | 44.3 | (43.3–45.2) | NA | 54.7 | (53.5–55.8) | NA | 63.1 | (61.0–65.1) | NA |
| Initial course of multiple sclerosis Relapsing– remitting | 1562 | 44.8 | (43.8–45.9) | Baseline comparator | 55.3 | (54.2–56.7) | Baseline comparator | 62.8 | (60.3–65.4) | Baseline comparator |
| Progressive | 282 | 42.1 | (40.2–44.0) | <0.001 | 53.0 | (51.1–54.9) | 0.002 | 63.1 | (60.0–66.2) | 0.24 |
a
Kurtzke Disability Status Scale (DSS) was used to determine the extent of disability.
b
p values were calculated using the log-rank test.
Adapted from Confavreux et al (2005a)
© 2006