Table 2.
Host genes affecting Ty1
| Gene name | Normal function/product | Function for Ty1 | Found by |
|---|---|---|---|
| Transcriptional effect genes | |||
| SPT3, 7, 8 | Transcription factor | Transcription initiation | Suppression of Ty- or LTR-induced mutation |
| SPT4, 5, 6 | Chromatin factors | Transcription initiation | Suppression of Ty- or LTR-induced mutation |
| SPT10, 21 | Repressor and activator | Repress 3′ LTR | Suppression of Ty- or LTR-induced mutation |
| Post transcriptional effect genes | |||
| IMT1-4 | Translation initiation, tRNAMeti | Prime reverse transcription | Intentional mutagenesis of genes to reveal interaction |
| (none) | tRNAArgCCU | Low level causes ribosome stalling, frameshifting | Search for genes which interfere with transposition when overexpressed |
| DBR1 | Debranch intron lariats (2′-5′ phosphodiesterase) | Unknown | Search for chromosomal mutations that interfere with transposition |