Table 1.

Human calicivirus classification and antigenic relationships among the caliciviruses

		Antigenic relationships
Genus	Virus straina	Determined by serologic IEM and/or crosschallenge studies in volunteers as described in the text	Determined by ELISA with hyperimmune antisera raised against recombinant Grimsby, Norwalk and Mexico virus-like particles
‘Norwalk-like viruses’	Norwalk	Distinct serotype	Distinct type
	Hawaii	Distinct serotype	Unknown
	Snow Mountain	Distinct serotype	Unknown
	Lorsdale	Unknown	Unknown (probably same as Grimsby)
	Southampton	Unknown	Unknown
	Mexico	Unknown	Distinct type
	Grimsby	Unknown	Distinct type
‘Sapporo-like viruses’	Sapporo	Distinct serotype	Unknown
	Manchester	Unknown	Unknown

^aOnly a representative subset of virus strains in each genus (‘Norwalk-like viruses’ and ‘Sapporo-like viruses’). See Green et al. (1999) for complete listing of strains.