Table 64-4.

Viral Diagnosis of Aseptic Meningitis Syndrome and Encephalitis

Virus	Tissue Culture	Antigen Detection	Serology
Adenovirus	+ + +	+	+ + +
Arboviruses	+ +	+	+ + +
Coronaviruses	+	+	+
Cytomegalovirus	+ + +	+ + +	+ + +
Enteroviruses	+ + +	+	+ +
Epstein-Barr virus	+	+	+ + +
Herpes simplex type 1	+ + +	+ +	+ + +
Herpes simplex type 2	+ + +	+ +	+ + +
Human herpesvirus 6	+ +	-	-
Human immunodeficiency virus	+ +	+ + +	+ + +
Influenza	+ +	+ +	+ + +
Lymphocytic choriomeningitis	+	+	+ +
Measles	+ +	+	+ + +
Mumps	+	+	+ +
Parainfluenza	+ + +	+ +	+
Rabies	+	+ +	+ +
Rotavirus	+	+ + +	+ + +
Rubella	+ +	+	+ + +
Varicella zoster virus	+ + +	+ +	+ + +
Symbols: +, method not available or research laboratory only; + +, method available in specialized reference laboratories; + + +, method used in most virology laboratories.