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. 2020 Feb 27;5(1):32–41. doi: 10.1089/can.2019.0003

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© Chris S. Breivogel et al. 2020; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited.

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FIG. 2. — Dose–response curves showing antinociceptive (top) and hypothermic (bottom) effects produced by THC (n=8), JWH-073 (n=10), and AM-2201 (n=8) in male C57BL/6 mice. Data shown were calculated as described in methods and are the mean±SEM of each parameter for each treatment group. Data were fit by nonlinear regression analysis using Prism with %MPE and change in temperature bottom set to 0 and %MPE top (E_max) set to 100%. %MPE, % maximum possible effect.