| Methods |
One site in Poland.
Two pretreatment and 12 treatment cycles.
Blinding not described. |
| Participants |
Healthy, normal‐weight, sexually active women aged 19 to 40 years seeking oral contraception with regular menses.
Excluded recent hormonal medication and certain other drugs; smokers; and contraindications to oral contraception. |
| Interventions |
EE 20 µg and desogestrel 150 µg versus EE 30 µg and gestodene 75 µg.
500 women randomized; initial number assigned to each study group not reported. |
| Outcomes |
Contraceptive efficacy, discontinuation, adverse events, and follicle growth.
Bleeding terms not defined. |
| Notes |
Allocated according to a randomization list in chronological order.
Excluded randomized women from the analysis.
63% (314/500) completed study. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
