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. 2014 Nov 17;2014(11):CD008726. doi: 10.1002/14651858.CD008726.pub2

Comparison 8. Cephalosporin (2nd generation B2) versus penicillins (ampicillin A4).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Maternal sepsis 1 75 Risk Ratio (M‐H, Fixed, 95% CI) 2.37 [0.10, 56.41]
2 Maternal endometritis 8 1890 Risk Ratio (M‐H, Fixed, 95% CI) 1.01 [0.75, 1.35]
3 Infant sepsis 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Infant oral thrush 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Maternal fever (febrile morbidity) 3 387 Risk Ratio (M‐H, Fixed, 95% CI) 1.17 [0.64, 2.15]
6 Maternal wound infection 5 638 Risk Ratio (M‐H, Fixed, 95% CI) 1.14 [0.47, 2.78]
7 Maternal urinary tract infection 4 462 Risk Ratio (M‐H, Random, 95% CI) 0.63 [0.11, 3.66]
8 Maternal thrush 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
9 Maternal composite serious infectious complication 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
10 Maternal composite adverse effects 3 1130 Risk Ratio (M‐H, Fixed, 95% CI) 1.92 [0.18, 20.82]
11 Maternal allergic reactions 1 176 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
12 Maternal nausea 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
13 Maternal vomiting 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
14 Maternal diarrhoea 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
15 Maternal skin rash 2 364 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.23, 4.46]
16 Immediate infant adverse effects 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
17 Infant unsettled 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
18 Infant diarrhoea 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
19 Infant skin rash 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
20 Development of bacterial resistance 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
21 Maternal length of hospital stay 0 0 Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
22 Infant length of hospital stay 0 0 Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
23 Infant's immune system development 0 0 Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
24 Infant general health 0 0 Std. Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
25 Infant frequency of hospital visits 0 0 Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
26 Costs 0 0 Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]